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Northwestern University Feinberg School of Medicine
Mesulam Center for Cognitive Neurology and Alzheimer’s Disease

Publications

  1. Chandra S, Vassar RJ  Gut microbiome-derived metabolites in Alzheimer's disease: Regulation of immunity and potential for therapeutics.  Immunol Rev  2024 Oct 23;. doi:10.1111/imr.13412
  2. Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber DE, Staffaroni AM, Geschwind DH  et al.  Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration.  Neurology  2024 Oct 22;103(8):e209832. pii:e209832
  3. Russo ML, Ayala G, Neal D, Rogalsky AE, Ahmad S, Musial TF, Pearlman M, Bean LA, Farooqi AK, Ahmed A  et al.  Alzheimer's-linked axonal changes accompany elevated antidromic action potential failure rate in aged mice.  Brain Res  2024 Oct 15;1841:149083. doi:10.1016/j.brainres.2024.149083
  4. Haynes G, Muhammad F, Weber KA, Khan AF, Hameed S, Shakir H, Van Hal M, Dickson D, Rohan M, Dhaher Y  et al.  Tract-specific magnetization transfer ratio provides insights into the severity of degenerative cervical myelopathy.  Spinal Cord  2024 Oct 01;. doi:10.1038/s41393-024-01036-y
  5. Arseni D, Nonaka T, Jacobsen MH, Murzin AG, Cracco L, Peak-Chew SY, Garringer HJ, Kawakami I, Suzuki H, Onaya M  et al.  Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C.  Nature  2024 Oct;634(8034):662-668. doi:10.1038/s41586-024-08024-5
  6. O'Conor R, Russell AM, Pack A, Oladejo D, Filec S, Rogalski E, Morhardt D, Lindquist LA, Wolf MS  Managing medications among individuals with mild cognitive impairment and dementia: Patient-caregiver perspectives.  J Am Geriatr Soc  2024 Oct;72(10):3011-3021. doi:10.1111/jgs.19065
  7. Castellani RJ, Jamshidi P  Cerebral amyloid-β-related angiitis and iatrogenic cerebral amyloid angiopathy-related vasculitis: Implications for amyloid-related imaging abnormalities.  J Neuropathol Exp Neurol  2024 Oct 01;83(10):890-892. doi:10.1093/jnen/nlae068
  8. Shi J, Touchon J, Middleton LT, Rovira MB, Vassar R, Vellas B, Shen Y  Now and future: Strategies for diagnosis, prevention and therapies for Alzheimer's disease.  Sci Bull (Beijing)  2024 Sep 28;. pii:S2095-9273(24)00715-1
  9. Sridharan PS, Koh Y, Miller E, Hu D, Chakraborty S, Tripathi SJ, Kee TR, Chaubey K, Vázquez-Rosa E, Barker S  et al.  Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury.  Cell Rep Med  2024 Sep 17;5(9):101715. pii:101715
  10. Fortington LV, Cassidy JD, Castellani RJ, Gardner AJ, McIntosh AS, Austen M, Kerr ZY, Quarrie KL  Epidemiological Principles in Claims of Causality: An Enquiry into Repetitive Head Impacts (RHI) and Chronic Traumatic Encephalopathy (CTE).  Sports Med  2024 Sep 15;. doi:10.1007/s40279-024-02102-4
  11. Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B  et al.  Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.  Nat Neurosci  2024 Sep;27(9):1668-1674. doi:10.1038/s41593-024-01730-3
  12. Barbieri E, Salvo JJ, Anderson NL, Simon S, Ables-Torres L, Los MA, Behn J, Bonakdarpour B, Holubecki AM, Braga RM  et al.  Progressive verbal apraxia of reading.  Cortex  2024 Sep;178:223-234. doi:10.1016/j.cortex.2024.06.011
  13. Reznicek J, Sharifai N, Jamshidi P, Wadhwani N, Ahrendsen JT  Embryonal and pineal tumours.  Cytopathology  2024 Sep;35(5):561-571. doi:10.1111/cyt.13350
  14. Plascencia-Villa G, Castellani RJ, Perry G  Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease.  Proc Natl Acad Sci U S A  2024 Aug 06;121(32):e2412255121. pii:e2412255121
  15. Høilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME  et al.  Donanemab, another anti-Alzheimer's drug with risk and uncertain benefit.  Ageing Res Rev  2024 Aug;99:102348. doi:10.1016/j.arr.2024.102348
  16. Zhang M, Ho E, Nowinski CJ, Fox RS, Ayturk E, Karpouzian-Rogers T, Novack M, Dodge HH, Weintraub S, Gershon R  The Paradox in Positive and Negative Aspects of Emotional Functioning Among Older Adults with Early Stages of Cognitive Impairment.  J Aging Health  2024 Aug;36(7-8):471-483. doi:10.1177/08982643231199806
  17. Smith H, Jean J, Duckett D, Vormittag-Nocito E, Nezami BG, Jennings LJ, Ahrendsen JT, Yang XJ, Primdahl D, Conway K  et al.  Diagnostic utility of multimodal advanced molecular testing to classify metastases of unknown primaries: A case of a patient with no known medical history.  J Neuropathol Exp Neurol  2024 Jul 31;. pii:nlae086
  18. Chandra S, Vassar R  The role of the gut microbiome in the regulation of astrocytes in Alzheimer's disease.  Neurotherapeutics  2024 Jul 24;:e00425. doi:10.1016/j.neurot.2024.e00425
  19. Mather MA, Ho EH, Bedjeti K, Karpouzian-Rogers T, Rogalski EJ, Gershon R, Weintraub S  Measuring Multidimensional Aspects of Health in the Oldest Old Using the NIH Toolbox: Results From the ARMADA Study.  Arch Clin Neuropsychol  2024 Jul 24;39(5):535-546. doi:10.1093/arclin/acad105
  20. Rajani RM, Ellingford R, Hellmuth M, Harris SS, Taso OS, Graykowski D, Lam FKW, Arber C, Fertan E, Danial JSH  et al.  Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.  PLoS Biol  2024 Jul;22(7):e3002727. pii:e3002727
  21. Kostelecky N, Wadhwani N, Golubovich I, Vormittag-Nocito E, Gao J, Jennings L, Caron M, Jamshidi P, Ahrendsen JT, Castellani R  et al.  Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma.  J Neuropathol Exp Neurol  2024 Jul 04;. pii:nlae075
  22. Chia R, Ray A, Shah Z, Ding J, Ruffo P, Fujita M, Menon V, Saez-Atienzar S, Reho P, Kaivola K  et al.  Genome sequence analyses identify novel risk loci for multiple system atrophy.  Neuron  2024 Jul 03;112(13):2142-2156.e5. doi:10.1016/j.neuron.2024.04.002
  23. Nassan M  Proposal for a Mechanistic Disease Conceptualization in Clinical Neurosciences: The Neural Network Components (NNC) Model.  Harv Rev Psychiatry  2024 Jul 01;32(4):150-159. doi:10.1097/HRP.0000000000000399
  24. Tyner CE, Boulton AJ, Slotkin J, Cohen ML, Weintraub S, Gershon RC, Tulsky DS  Exploring symptom clusters in mild cognitive impairment and dementia with the NIH Toolbox.  J Int Neuropsychol Soc  2024 Jul;30(6):603-614. doi:10.1017/S1355617724000055
  25. Cahan J, Finley JA, Cotton E, Orban ZS, Jimenez M, Weintraub S, Sorets T, Koralnik IJ  Cognitive functioning in patients with neuro-PASC: the role of fatigue, mood, and hospitalization status.  Front Neurol  2024;15:1401796. pii:1401796
  26. McCord M, Jamshidi P  Targeting the cell cycle to enhance chemotherapy efficacy in glioblastoma.  Neuro Oncol  2024 Jun 03;26(6):1097-1098. doi:10.1093/neuonc/noae062
  27. Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC  et al.  MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.  Lancet Neurol  2024 May;23(5):487-499. doi:10.1016/S1474-4422(24)00083-8
  28. Ayala I, Bahrami A, Pan Y, Spencer C, Flanagan ME, Mesulam MM, Gefen T, Geula C  Loss and microglia phagocytosis of synaptic proteins in frontotemporal lobar degeneration with TDP-43 proteinopathy.  Neurochem Int  2024 May;175:105719. doi:10.1016/j.neuint.2024.105719
  29. Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber D, Staffaroni AM, Geschwind D  et al.  Gene specific effects on brain volume and cognition of TMEM106B in frontotemporal lobar degeneration.  medRxiv  2024 Apr 05;. pii:2024.04.05.24305253
  30. Iverson GL, Gardner AJ, Castellani RJ, Kissinger-Knox A  Applying the Consensus Criteria for Traumatic Encephalopathy Syndrome Retrospectively to Case Studies of Boxers from the 20th Century.  Neurotrauma Rep  2024;5(1):337-347. doi:10.1089/neur.2023.0134
  31. Høilund-Carlsen PF, Alavi A, Castellani RJ, Neve RL, Perry G, Revheim ME, Barrio JR  Alzheimer's Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?  Int J Mol Sci  2024 Mar 31;25(7). pii:3892
  32. Turner M, Belli A, Castellani RJ  Changes in Brain Structure and Function in a Multisport Cohort of Retired Female and Male Athletes, Many Years after Suffering a Concussion: Implications for Neuroplasticity and Neurodegenerative Disease Pathogenesis.  J Alzheimers Dis Rep  2024;8(1):501-516. doi:10.3233/ADR-240021
  33. Kawles A, Keszycki R, Minogue G, Zouridakis A, Ayala I, Gill N, Macomber A, Lubbat V, Coventry C, Rogalski E  et al.  Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias.  Acta Neuropathol Commun  2024 Feb 22;12(1):31. pii:31
  34. Walenski M, Sostarics T, Mesulam MM, Thompson CK  The production of adjectives in narratives by individuals with primary progressive aphasia.  J Neurolinguistics  2024 Feb;69. pii:101179
  35. Paudel B, Jeong SY, Martinez CP, Rickman A, Haluck-Kangas A, Bartom ET, Fredriksen K, Affaneh A, Kessler JA, Mazzulli JR  et al.  Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging.  Nat Commun  2024 Jan 18;15(1):264. pii:264
  36. Watkins EA, Vassar R  BACE Inhibitor Clinical Trials for Alzheimer's Disease.  J Alzheimers Dis  2024;101(s1):S41-S52. doi:10.3233/JAD-231258
  37. Høilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME  et al.  Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village.  Ageing Res Rev  2024 Jan;93:102173. doi:10.1016/j.arr.2023.102173
  38. Echevarria-Cooper SL, Ho EH, Gershon RC, Weintraub S, Kahnt T  Evaluation of the NIH Toolbox Odor Identification Test across normal cognition, amnestic mild cognitive impairment, and dementia due to Alzheimer's disease.  Alzheimers Dement  2024 Jan;20(1):288-300. doi:10.1002/alz.13426
  39. Petersen RC, Weintraub S, Sabbagh M, Karlawish J, Adler CH, Dilworth-Anderson P, Frank L, Huling Hummel C, Taylor A,   A New Framework for Dementia Nomenclature.  JAMA Neurol  2023 Dec 01;80(12):1364-1370. doi:10.1001/jamaneurol.2023.3664
  40. Minogue G, Kawles A, Zouridakis A, Keszycki R, Macomber A, Lubbat V, Gill N, Mao Q, Flanagan ME, Zhang H  et al.  Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with Transactive Response DNA-binding Protein 43.  Ann Neurol  2023 Dec;94(6):1036-1047. doi:10.1002/ana.26762
  41. Zouridakis A, Ayala I, Minogue G, Kawles A, Keszycki R, Macomber A, Bigio EH, Geula C, Mesulam MM, Gefen T  Shades of gray in human white matter.  J Comp Neurol  2023 Dec;531(18):2109-2120. doi:10.1002/cne.25512
  42. Franzen S, Nuytemans K, Bourdage R, Caramelli P, Ellajosyula R, Finger E, Illán-Gala I, Loi SM, Morhardt D, Pijnenburg Y  et al.  Gaps in clinical research in frontotemporal dementia: A call for diversity and disparities-focused research.  Alzheimers Dement  2023 Dec;19(12):5817-5836. doi:10.1002/alz.13129
  43. McCord M, Jamshidi P, Thirunavu V, Santana-Santos L, Vormittag-Nocito E, Dittman D, Parker S, Baczkowski J, Jennings L, Walshon J  et al.  Variant allelic frequencies of driver mutations can identify gliomas with potentially false-negative MGMT promoter methylation results.  Acta Neuropathol Commun  2023 Nov 02;11(1):175. pii:175
  44. Lapins A, Bonakdarpour B  The case of a 60-year-old man with decline in job performance and changes in personality and judgment.  Ann Clin Transl Neurol  2023 Nov;10(11):2171-2172. doi:10.1002/acn3.51917
  45. Engelmeyer JR, Kerr A, Makowski-Woidan BA, Gill NP, Mesulam MM, Weintraub S, Zhang H, Lindquist L, Rogalski EJ  Medical characterization of cognitive SuperAgers: Investigating the medication profile of SuperAgers.  J Am Geriatr Soc  2023 Nov;71(11):3638-3641. doi:10.1111/jgs.18496
  46. Hammers DB, Nemes S, Diedrich T, Eloyan A, Kirby K, Aisen P, Kramer J, Nudelman K, Foroud T, Rumbaugh M  et al.  Learning slopes in early-onset Alzheimer's disease.  Alzheimers Dement  2023 Nov;19 Suppl 9(Suppl 9):S19-S28. doi:10.1002/alz.13159
  47. Pang L, Dunterman M, Guo S, Khan F, Liu Y, Taefi E, Bahrami A, Geula C, Hsu WH, Horbinski C  et al.  Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma.  Nat Immunol  2023 Oct;24(10):1654-1670. doi:10.1038/s41590-023-01605-y
  48. Gasca-Salas C, Duff-Canning S, McArthur E, Armstrong MJ, Fox S, Meaney CA, Tang-Wai DF, Gill D, Eslinger PJ, Zadikoff C  et al.  Predictors of Cognitive Change in Parkinson Disease: A 2-year Follow-up Study.  Alzheimer Dis Assoc Disord  ;37(4):335-342. doi:10.1097/WAD.0000000000000576
  49. Zhang L, Flagan TM, Häkkinen S, Chu SA, Brown JA, Lee AJ, Pasquini L, Mandelli ML, Gorno-Tempini ML, Sturm VE  et al.  Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum.  Ann Neurol  2023 Oct;94(4):632-646. doi:10.1002/ana.26738
  50. Upadhyay A, Chhangani D, Rao NR, Kofler J, Vassar R, Rincon-Limas DE, Savas JN  Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity.  Mol Neurodegener  2023 Sep 14;18(1):61. pii:61

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